Authors
Cosmas Rinaldi Adithya Lesmana, Akash Shukla, Ashish Kumar, Shalimar, Xiaolong Qi, Rino Alvani Gani, Ze-Hao Zhuang, Abdul Kadir Dokmeci, Gin Ho Lo, Hitoshi Maruyama, Ji-Dong Jia, Anand V Kulkarni, Jason Chang, Necati Ormeci, Gamal Shiha, Hasnain Ali Shah, Jose D Sollano, Sahaj Rathi, Tan Soek Siam, George K Lau, Rungsun Rerknimitr, Ming-Chih Hou, Juferdy Kurniawan, Guohong Han, Amar Mukund, Sanjay Saran Baijal, Shiv Kumar Sarin
Published in
Hepatology international. Aug 31, 2025. Epub Aug 31, 2025.
Abstract
Acute variceal bleeding (AVB) is a common life-threatening complication of portal hypertension (PHT), having a six-week mortality of 10%-20%. Major advances in the hemodynamic management, risk stratification, pharmacotherapy, endoscopy techniques, hemostatic devices and radiological interventions have led to improved management and outcome of AVB patients in the recent past. Therefore, the APASL Portal Hypertension Working Party, chose a panel of experts, primarily from the Asia-Pacific region, to identify important developments and controversial areas in the field of AVB. They discussed through a pre-defined and structured process, advances in the field and proposed updates to the previous APASL AVB guidelines. These included emphasis on safe transportation, defining time frames for AVB episodes and re-bleeding, reporting of clinical outcomes, optimizing early intervention strategies, pharmacotherapy, medical management, endoscopic therapies, and salvage modalities, including TIPS and self-expanding metal stents. The current updates also cover variceal bleeding in special populations and situations, the skill sets required for managing AVB patients, and the research priorities in the field. The updated guidelines are based on the latest evidence and incorporate emerging trends to provide a contemporary template for management of AVB in both patients with cirrhosis and non-cirrhotic portal hypertension.
PMID:
40886248
Bibliographic data and abstract were imported from PubMed on 31 Aug 2025.
Read full publication at:
Please sign in
to see all details.
Stats
- Recommendations n/a n/a positive of 0 vote(s)
- Views 17
- Comments 0