Published in
Nature, Nature Publishing Group
Content
Nature, Published online: 27 August 2025; doi:10.1038/s41586-025-09388-y
Aminoacyl-thiols reacting selectively with RNA diols over amine nucleophiles and demonstration of chemically controlled formation of peptidyl-RNA in water at neutral pH suggest an important role for thiol cofactors before the evolution of enzymes.
Matthew W. Powner
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