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Face off: Stem cell therapy versus the immune system

Journal content Created on 04 Sep 2025 by Cell Stem Cell

Published in

Cell Stem Cell, Cell Press (Reed Elsevier)

Content

As stem cell therapies make great strides in clinical trials, the challenge of immune rejection has come into a sharper focus. Several recent clinical reports provide insight into the challenges posed by HLA mismatch and immunosuppression. Immunological analyses accompanying recent cell therapy trials suggest strategies that may mitigate these risks.

Roberto Castro-Gutierrez, Qizhi Tang

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