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Noncoding rare variant associations with blood traits in 166,740 UK Biobank genomes

Journal content Created on 06 Aug 2025 by Nature Genetics

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Nature Genetics, Nature Publishing Group

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Nature Genetics, Published online: 06 August 2025; doi:10.1038/s41588-025-02288-x

Noncoding rare variant analyses using whole-genome sequencing data from the UK Biobank identify gene–trait associations for 42 blood cell traits but find that most signals are driven by linkage disequilibrium between common and rare variants.

Olivier Delaneau

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