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Evolutionarily conserved role of telomerase reverse transcriptase in programming the microenvironment via regulation of the cGAS–STING pathway

Journal content Created on 06 Aug 2025 by Nature Cell Biology

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Nature Cell Biology, Nature Publishing Group

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Nature Cell Biology, Published online: 06 August 2025; doi:10.1038/s41556-025-01706-w

Akincilar, Fidan et al. report a conserved role for telomerase reverse transcriptase in regulating inflammation via the cGAS–STING nucleic acid-sensing pathway in myeloid cells, independent of its telomerase activity.

Vinay Tergaonkar

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