[Articles] Metastasis-directed radiotherapy without systemic therapy for oligometastatic clear-cell renal-cell carcinoma: primary efficacy analysis of a single-arm, single-centre, phase 2 trial

Journal content Created on 05 Sep 2025 by The Lancet Oncology

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The Lancet Oncology, The Lancet (Reed Elsevier)

Content

Select patients with oligometastatic disease can be managed with serial metastasis-directed therapy with prolonged time off systemic therapy, favourable progression-free survival, and limited adverse events.

Chad Tang, Alexander D Sherry, Aaron Seo, Kieko Hara, Haesun Choi, Suyu Liu, Xiaowen Sun, Anya Montoya, Ethan B Ludmir, Amishi Y Shah, Eric Jonasch, Amado J Zurita, Craig Kovitz, Omar Alhalabi, Sangeeta Goswami, Andrew W Hahn, Matthew T Campbell, Arianna Hernandez, Kevin T Nead, Peter Van Loo, Shiqin Su, Christopher J Battey, Matthew L LaBella, Sarah Ratzel, Ashley Acevedo, Giannicola Genovese, Kanishka Sircar, Jose A Karam, Nizar M Tannir, Pavlos Msaouel

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