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Tissue-specific mRNA delivery and prime editing with peptide–ionizable lipid nanoparticles

Journal content Created on 01 Sep 2025 by Nature Materials

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Nature Materials, Nature Publishing Group

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Nature Materials, Published online: 01 September 2025; doi:10.1038/s41563-025-02320-9

Peptide ionizable lipids containing specific amino acids and functional groups render lipid nanoparticles with the tissue-specific delivery of mRNA and prime editing systems, which can be useful for advanced mRNA-based therapeutics.

Qiang Cheng

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